How many neurology and CNS biotech drugs are in clinical development?

BioRadar is tracking 118 neurology and CNS drug programs across 17 public biotech companies, including 20 in Phase 3. Coverage focuses on companies with active FDA catalysts and updates automatically.

Which biotech companies are developing neurology and CNS drugs?

The most active companies by program count in this area are BIIB, LLY, AXSM, CYTK, BHVN, IONS. Each has a dedicated BioRadar page with its pipeline, upcoming FDA dates and cash runway.

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Neurology & CNS Biotech Pipeline: Brain and Nervous System Drugs

Every neurology and CNS program BioRadar tracks across 17 public biotech companies — drug candidates, trial phases and upcoming FDA decisions. Updated automatically.

Pipelines by area: Oncology Infectious DiseaseNeurology / CNSObesity / Metabolic

BioRadar is tracking 118 neurology and CNS drug programs across 17 public companies, with 2 upcoming FDA decisions in this area. The most active companies by program count are BIIB, LLY, AXSM, CYTK, BHVN.

118Drug programs

17Companies

20In Phase 3

2Upcoming FDA dates

Upcoming FDA decisions in Neurology & CNS

Date	Ticker	Drug / Indication	Type	In
Nov 14, 2026	BTAI	agitation associated with Alzheime	sNDA	52d
May 1, 2027	AXSM	agitation associated with dementia	NDA	220d

See all upcoming FDA decisions →

Companies with neurology and CNS programs

BIIB 37 programs LLY 15 programs AXSM 9 programs CYTK 8 programs BHVN 7 programs IONS 7 programs JAZZ 6 programs ACIU 5 programs BTAI 5 programs VRTX 5 programs CORT 3 programs TLSA 3 programs ARWR 2 programs CMPS 2 programs GILD 2 programs OMER 1 program VKTX 1 program

Phase 3 neurology & cns programs (20)

Ticker	Drug	Indication
AXSM	AXS-07 (MoSEIC meloxicam and rizatriptan	Migraine
AXSM	AXS-07 (meloxicam-rizatriptan)	Migraine
AXSM	AXS-07	Migraine
AXSM	Meloxicam	Migraine
AXSM	Rizatriptan	Migraine
BIIB	Lecanemab IV	Early Alzheimer's Disease
BIIB	Lecanemab SC	Early Alzheimer's Disease
BIIB	Lecanemab	Preclinical Alzheimer's Disease
BIIB	Interferon β-1a	Relapsing-Remitting Multiple Sclerosis
CMPS	Psilocybin	Treatment Resistant Depression
CYTK	tirasemtiv	Amyotrophic Lateral Sclerosis
IONS	ION363	Amyotrophic Lateral Sclerosis
IONS	Eplontersen	Hereditary Transthyretin-Mediated Amyloid Polyneur
IONS	Tofersen	ALS Caused by Superoxide Dismutase 1 (SOD1) Mutati
IONS	Inotersen	Hereditary Transthyretin-Mediated Amyloid Polyneur
JAZZ	Xywav	Narcolepsy
LLY	Lepodisiran	Atherosclerosis
LLY	Donanemab	Alzheimer Disease
LLY	Lasmiditan	Migraine
VRTX	Pregabalin	Diabetic Peripheral Neuropathic Pain

Phase 2 neurology & cns programs (35)

Ticker	Drug	Indication
ACIU	ACI-7104.056 at Dose A	Parkinson Disease
ACIU	ACI-7104.056 at Dose C (optional)	Parkinson Disease
ACIU	ACI-7104.056 at Dose B (optional)	Parkinson Disease
AXSM	AXS-12 (reboxetine)	Narcolepsy
BHVN	BHV-7000	Focal Epilepsy
BHVN	BHV-2100	Migraine
BHVN	BHV-8000	Parkinson Disease
BHVN	BHV-8000 20 mg	Parkinson Disease
BHVN	BHV-8000 10mg	Parkinson Disease
BIIB	Lecanemab 5.0 mg/kg	Alzheimer's Disease
BIIB	Lecanemab 2.5 mg/kg	Alzheimer's Disease
BIIB	Lecanemab 10 mg/kg	Alzheimer's Disease
BIIB	DRF	Relapsing Forms of Multiple Sclerosis
BIIB	BIIB091	Relapsing Forms of Multiple Sclerosis
BIIB	BIIB122 225 mg	Parkinson Disease
BIIB	Tyruko Injectable Product	Multiple Sclerosis
BIIB	RTA 901	Diabetic Peripheral Neuropathic Pain
BIIB	BIIB122	Parkinson Disease
BIIB	Diranersen	Mild Cognitive Impairment Due to Alzheimer's Disea
CMPS	CTX-471	Neuroendocrine Neoplasm
CORT	Dazucorilant 300 mg	Amyotrophic Lateral Sclerosis
CORT	Dazucorilant 150 mg	Amyotrophic Lateral Sclerosis
CORT	Dazucorilant	Amyotrophic Lateral Sclerosis
CYTK	Riluzole	Amyotrophic Lateral Sclerosis
CYTK	CK-2017357	Amyotrophic Lateral Sclerosis
CYTK	CK-2017357 (Part A)	Amyotrophic Lateral Sclerosis
CYTK	CK-2017357 (Part B)	Amyotrophic Lateral Sclerosis
CYTK	Riluzole 50 MG (Part B)	Amyotrophic Lateral Sclerosis
CYTK	Riluzole 50 MG	Amyotrophic Lateral Sclerosis
JAZZ	JZP926 capsule	Juvenile Myoclonic Epilepsy
LLY	Clazakizumab	Atherosclerosis
OMER	OMS643762	Huntington's Disease
TLSA	Foralumab	Secondary Progressive Multiple Sclerosis
TLSA	Foralumab TZLS-401 100 µg	Non-Active Secondary Progressive Multiple Sclerosi
VRTX	VX-993	Diabetic Peripheral Neuropathic Pain

Phase 1 neurology & cns programs (31)

Ticker	Drug	Indication
ACIU	ACI-35.030	Alzheimer's Disease
ACIU	JACI-35.054	Alzheimer's Disease
ARWR	ARO-MAPT-SC	Alzheimer Disease
ARWR	ARO-SOD1 Injection	Amyotrophic Lateral Sclerosis
AXSM	Solriamfetol 150 mg Oral Tablet	Narcolepsy
BHVN	BHV-700	Epilepsy
BTAI	BXCL501 60 Micrograms	Schizophrenia
BTAI	BXCL501 120 Micrograms	Schizophrenia
BTAI	BXCL501 80 Micrograms	Schizophrenia
CYTK	Moxifloxacin	QT Intervals Changes
GILD	KITE-363	Chronic Inflammatory Demyelinating Polyneuropathy
GILD	GPC2 CAR T cells	Refractory Neuroblastoma
IONS	ION269	Alzheimer Disease
IONS	BIIB094	Parkinson's Disease
IONS	IONIS MAPTRx	Mild Alzheimer's Disease
JAZZ	JZP441	Narcolepsy
LLY	Cyclophosphamide	Neuroblastoma
LLY	LY3439539	Alzheimer Disease
LLY	Methylprednisolone	Parkinson Disease
LLY	Sirolimus	Parkinson Disease
LLY	LY3295668 Erbumine	Neuroblastoma
LLY	Flortaucipir F18	Alzheimer Disease
LLY	LY3954068	Alzheimer Disease
LLY	LY4256984	Amyotrophic Lateral Sclerosis
LLY	LY4286533	Neuropathic Pain
LLY	LY3884961	Parkinson Disease
TLSA	Intranasal Foralumab Solution	Primary Progressive Multiple Sclerosis
VKTX	VK0214	Adrenomyeloneuropathy Form (AMN) of X-linked Adren
VRTX	Midazolam	Narcolepsy Type 1 (NT1)
VRTX	VX-433	Narcolepsy Type 1 (NT1)
VRTX	Bupropion	Narcolepsy Type 1 (NT1)

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Data: ClinicalTrials.gov, SEC & FDA filings • Informational only, not investment advice. • All biotech stocks A–Z →