Company guidance, FDA catalysts, dilution risk and cash runway, built from SEC, FDA and ClinicalTrials.gov filings and updated every day.
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| Drug | Indication | Most advanced trial | Status |
|---|---|---|---|
| Benzgalantamine FDA approved Jul 2024 · Zunveyl |
Alzheimer Disease | Phase 4 · NCT07633470 | Recruiting |
| Zorifertinib (AZD3759) | Non-small Cell Lung Cancer | Phase 2/3 · NCT03653546 | Completed |
| Birinapant | High Grade Fallopian Tube Serous Adenocarcinoma | Phase 1/2 · NCT02756130 | Withdrawn |
| [14C]Zorifertinib Oral Formulation | EGFR Mutant Advanced Non-small Cell Lung Cancer | Phase 1 · NCT07620951 | Completed |
| [211At]NaAt | DTC - Differentiated Thyroid Cancer | Phase 1 · NCT07287748 | Recruiting |
Also used in these trials (approved or third-party drugs, not ACOG's own candidates): Pembrolizumab, Erlotinib Hydrochloride, Gefitinib, Trifluridine And Tipiracil, Carboplatin.
Source: ClinicalTrials.gov trials sponsored by the company, one row per candidate at its most advanced registered trial. FDA approvals: Drugs@FDA. Wrong or missing drug? Report it
ACOG holds $41.4M in cash and short-term investments (as of Jun 30, 2026) and burns about $9.3M/quarter from operations, an estimated runway of 13.3 months at that rate (BioRadar estimate, not company guidance).
Dilution pressure: 57 · Elevated
Recent financing filings on SEC EDGAR:
Source: SEC EDGAR (XBRL cash flow and financing filings). Dilution Watch: every company ranked → · Get an alert when ACOG files for a raise →
| Holder | Type | Shares | % of shares | As of |
|---|---|---|---|---|
| Opaleye Management Inc. 10% owner |
Insider | 3,322,954 | 15.26% | 2026-10-01 |
| AWM Investment Company, Inc. | Institution (13G, 5%+) | 2,172,036 | 9.97% | 2025-12-31 |
| James E. Besser | 5%+ holder (13G) | 1,639,255 | 7.53% | 2026-07-14 |
| MANCHESTER MANAGEMENT COMPANY, LLC | 5%+ holder (13G) | 1,127,181 | 5.18% | 2025-12-30 |
| Funicular Funds, LP | 5%+ holder (13G) | 1,114,747 | 5.12% | 2026-02-11 |
| Leonard Powell Mertz Director · +8,437 options |
Insider | 267,239 | 1.23% | 2026-01-14 |
| Kenneth Anthony Cawkell Director · +8,437 options |
Insider | 225,717 | 1.04% | 2026-01-14 |
| Michael E. McFadden Chief Executive Officer, Director · +253,796 options |
Insider | 204,691 | 0.94% | 2026-01-09 |
| Lauren D'Angelo Chief Operating Officer · +106,545 options |
Insider | 140,695 | 0.65% | 2026-05-19 |
| Phillip Joseph Mertz Director · +8,437 options |
Insider | 42,263 | 0.19% | 2026-01-14 |
| Robert James Wills Director · +8,437 options |
Insider | 32,241 | 0.15% | 2026-08-21 |
| Henry Huy Du VP Finance and Accounting · +15,982 options |
Insider | 20,579 | 0.09% | 2026-01-09 |
Share count 21,777,868 (latest 10-Q/10-K). Insiders: each officer's, director's and 10% owner's latest Form 3, 4 or 5, direct and indirect shares; options are not counted. 5%+ holders: latest Schedule 13D or 13G of each holder above 5%. Institutions: the total held by all 13F filers (Yahoo Finance); the table lists the largest. Sources have different dates, so the split is approximate. Source: SEC EDGAR.
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