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Obesity & Metabolic Biotech Pipeline: Weight Loss and Diabetes Drugs
Every obesity and metabolic disease program BioRadar tracks across 12 public biotech companies — drug candidates, trial phases and upcoming FDA decisions. Updated automatically.
BioRadar is tracking 59 obesity and metabolic disease drug programs across 12 public companies. The most active companies by program count are LLY, CORT, ARWR, GILD, VRTX.
Companies with obesity and metabolic disease programs
Phase 3 obesity & metabolic programs (11)
| Ticker | Drug | Indication |
|---|---|---|
| ARWR | Zodasiran | Homozygous Familial Hypercholesterolemia |
| ARWR | zodasiran Injection | Homozygous Familial Hypercholesterolemia |
| LLY | Semaglutide | Type 2 Diabetes |
| LLY | Retatrutide | Metabolic Dysfunction-Associated Steatotic Liver D |
| LLY | Eloralintide | Overweight |
| LLY | Tirzepatide | Obesity |
| VKTX | VK2735 | Weight Loss |
| VRTX | Pregabalin | Diabetic Peripheral Neuropathic Pain |
| VRTX | Biological/Vaccine | Type 1 Diabetes |
| VRTX | VX-017 | Diabetes Mellitus, Type 1 |
| VRTX | VX-880 | Diabetes Mellitus, Type 1 |
Phase 2 obesity & metabolic programs (25)
| Ticker | Drug | Indication |
|---|---|---|
| ARWR | ARO-APOC3 | Dyslipidemias |
| ARWR | ARO-ANG 3 Injection | Homozygous Familial Hypercholesterolemia |
| ARWR | ARO-ANG3 | Mixed Dyslipidemia |
| BHVN | taldefgrobep alfa | Obesity |
| BIIB | RTA 901 | Diabetic Peripheral Neuropathic Pain |
| CORT | Miricorlilant | Antipsychotic-induced Weight Gain (AIWG) |
| CORT | Miricorilant (Cohort B) | Nonalcoholic Steatohepatitis (NASH) |
| CORT | Miricorilant (Cohort A) | Nonalcoholic Steatohepatitis (NASH) |
| CORT | Miricorilant | Antipsychotic-induced Weight Gain (AIWG) |
| GILD | Actos | Type 2 Diabetes Mellitus |
| GILD | MBX-2982 | Diabetes |
| GILD | Sitagliptin | Diabetes |
| GILD | Metformin | Type 2 Diabetes Mellitus |
| GILD | MBX-102 | Type 2 Diabetes Mellitus |
| LLY | Lisdexamfetamine Dimesylate | Obesity and Overweight |
| LLY | LY3532226 | Obesity |
| LLY | LY3305677 | Obesity |
| LLY | Macupatide | Obesity |
| LLY | LY3841136 | Obesity |
| LLY | LY3457263 | Type 2 Diabetes |
| SRRK | Tirzepatide | Overweight and Obesity |
| TLSA | Omeprazole 20mg | NASH - Nonalcoholic Steatohepatitis |
| VERU | Semaglutide (Wegovy) weekly injection | Obesity & Overweight |
| VKTX | VK2809 | NASH - Nonalcoholic Steatohepatitis |
| VRTX | VX-993 | Diabetic Peripheral Neuropathic Pain |
Phase 1 obesity & metabolic programs (23)
| Ticker | Drug | Indication |
|---|---|---|
| ARWR | sterile normal saline (0.9% NaCl) | Dyslipidemias |
| ARWR | ARO-INHBE | Obesity |
| ARWR | Tirzepatide | Obesity |
| ARWR | ARO-ALK7 | Obesity |
| ARWR | ARO-DIMERPA | Hyperlipidemia; Mixed |
| CORT | CORT118335 | Antipsychotic-induced Weight Gain |
| CORT | Olanzapine | Antipsychotic-induced Weight Gain |
| CORT | Fluvoxamine | Antipsychotic Induced Weight Gain |
| CORT | Miricorilant 150 mg | Nonalcoholic Steatohepatitis (NASH) |
| CORT | Miricorilant 50 mg | Nonalcoholic Steatohepatitis (NASH) |
| CORT | Miricorilant 10 mg | Nonalcoholic Steatohepatitis (NASH) |
| CORT | Miricorilant 100 mg | Nonalcoholic Steatohepatitis (NASH) |
| GILD | Omeprazole | Weight Management |
| GILD | GS-4571 | Weight Management |
| LLY | LY4329090 | Obesity |
| LLY | Combined oral contraceptive | Obesity |
| LLY | LY4174794 | Obesity |
| LLY | Acetaminophen | Diabetes Mellitus, Type 1 |
| LLY | LY4064912 | Overweight or Obesity |
| LLY | Dulaglutide | Type 2 Diabetes Mellitus (T2DM) |
| SPRO | Tebipenem Pivoxil Hydrobromide | Diabetes |
| VKTX | VK2735 Drug | Weight Loss |
| VRTX | VX-264 | Type 1 Diabetes |
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