Company guidance, FDA catalysts, dilution risk and cash runway, built from SEC, FDA and ClinicalTrials.gov filings and updated every day.
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Quoted word for word from the company's press releases filed with the SEC. Timing is the company's own guidance, not a BioRadar estimate.
| Drug | Indication | Most advanced trial | Status |
|---|---|---|---|
| Pimavanserin Tartrate FDA approved Apr 2016 · Nuplazid |
Parkinson's Disease Psychosis | Phase 3 · NCT01174004 | Completed |
| Trofinetide FDA approved Mar 2023 · Daybue |
Rett Syndrome | Phase 3 · NCT04776746 | Terminated |
| ACP-204 | Lewy Body Dementia Psychosis | Phase 3 · NCT07095465 | Recruiting |
| Carbetocin | Hyperphagia in Prader-Willi Syndrome | Phase 3 · NCT06173531 | Active not recruiting |
| ACP-044 Dose A | Osteoarthritis Pain | Phase 2 · NCT05008835 | Terminated |
| ACP-044 Dose B | Osteoarthritis Pain | Phase 2 · NCT05008835 | Terminated |
| ACP-104 | Schizophrenia | Phase 2 · NCT00490516 | Completed |
| ACP-211 | Major Depressive Disorder (MDD) | Phase 2 · NCT07284667 | Recruiting |
| Active drug: pimavanserin 17mg (2 streng | Parkinson Disease | Phase 2 · NCT03947216 | Completed |
| Pimavanserin 34 milligrams (MG) [Nuplazi | Schizophrenia | Phase 2 · NCT03994965 | Withdrawn |
Also used in these trials (approved or third-party drugs, not ACAD's own candidates): Pimavanserin, Quetiapine.
Source: ClinicalTrials.gov trials sponsored by the company, one row per candidate at its most advanced registered trial. FDA approvals: Drugs@FDA. Wrong or missing drug? Report it
ACAD holds $956.5M in cash and short-term investments (as of Jun 30, 2026) and its operations are currently cash-flow neutral or positive.
Dilution pressure: 0 · Low
Source: SEC EDGAR (XBRL cash flow and financing filings). Dilution Watch: every company ranked → · Get an alert when ACAD files for a raise →
| Holder | Type | Shares | % of shares | As of |
|---|---|---|---|---|
| Julian C. Baker | Institution (13G, 5%+) | 43,294,373 | 25.13% | 2026-02-24 |
| BAKER BROS. ADVISORS LP Director, 10% owner · +32,008 options |
Insider | 39,487,463 | 22.92% | 2026-05-29 |
| STATE STREET CORPORATION | Institution (13G, 5%+) | 9,076,212 | 5.27% | 2026-06-30 |
| Vanguard Portfolio Management | Institution (13G, 5%+) | 8,781,007 | 5.10% | 2026-03-31 |
| Mark C. Schneyer EVP, CHIEF FINANCIAL OFFICER · +157,929 options |
Insider | 67,828 | 0.04% | 2026-08-05 |
| Daniel B Soland Director · +21,900 options |
Insider | 44,041 | 0.03% | 2025-05-29 |
| Edmund Harrigan Director · +39,108 options |
Insider | 43,148 | 0.03% | 2026-05-29 |
| Elizabeth A. Garofalo Director · +39,108 options |
Insider | 33,489 | 0.02% | 2026-05-29 |
| Adora Ndu Director · +39,108 options |
Insider | 32,908 | 0.02% | 2026-05-29 |
| Laura Brege Director · +25,315 options |
Insider | 23,202 | 0.01% | 2026-05-29 |
| Elizabeth H.Z. Thompson EVP, Head of Research & Dev · +133,846 options |
Insider | 18,994 | 0.01% | 2026-07-29 |
| Adams Catherine Owen Chief Executive Officer, Director · +333,535 options |
Insider | 14,803 | 0.01% | 2026-03-24 |
Share count 172,305,518 (latest 10-Q/10-K). Insiders: each officer's, director's and 10% owner's latest Form 3, 4 or 5, direct and indirect shares; options are not counted. 5%+ holders: latest Schedule 13D or 13G of each holder above 5%. Institutions: the total held by all 13F filers (Yahoo Finance); the table lists the largest. Sources have different dates, so the split is approximate. Source: SEC EDGAR.
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