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ARO-INHBE

Oligonucleotide (siRNA) · Gene silencing: INHBE · developed by ARROWHEAD PHARMACEUTICALS

Phase 1/2 Most advanced trial

ARWR Developer

1 Registered trials

What is ARO-INHBE?

ARO-INHBE is an siRNA therapeutic that silences INHBE (inhibin beta E subunit) expression. It is being studied in obesity.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Oligonucleotide (siRNA)
Targets: INHBE
Mechanism: Gene silencing: INHBE
Therapy area: Metabolic
Developer: ARROWHEAD PHARMACEUTICALS (ARWR)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1/2

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT06700538	Phase 1/2	Obesity	Recruiting	ARWR

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Obesity

More from ARROWHEAD PHARMACEUTICALS

Plozasiran FDA approved ARC-521 Phase 1 ARC-AAT Phase 2 ARO-033 Phase 1 ARO-ALK7 Phase 1/2 ARO-ANG 3 Phase 2 ARO-APOC3 Phase 2 ARO-ATXN2 Phase 1 ARO-C3 Phase 1/2 ARO-CFB Phase 1 ARO-DIMERPA Phase 1/2 ARO-ENaC Phase 1/2

Sources

ClinicalTrials.gov NCT06700538

Updated Oct 3, 2026. Something wrong or missing? Report it on the ARWR page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z