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COVID-HIG · NP-028

Plasma-derived product · Immune activation, directed at SARS-CoV-2 spike protein · developed by Emergent BioSolutions

Phase 1 Most advanced trial (none active)

EBS Developer

1 Registered trials

What is COVID-HIG?

COVID-HIG is a purified liquid immunoglobulin G (IgG) preparation derived from human plasma containing anti-SARS-CoV-2 antibodies. It is studied for the treatment of SARS-CoV-2 infection.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as: NP-028
Drug type: Plasma-derived product
Targets: SARS-CoV-2 spike protein
Mechanism: Immune activation, directed at SARS-CoV-2 spike protein
Therapy area: Infectious disease
Developer: Emergent BioSolutions (EBS)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1
UNII: VF62JD6WN3

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT05142306	Phase 1	SARS-CoV-2 Infection	Completed	EBS

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

SARS-CoV-2 Infection

More from Emergent BioSolutions

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Sources

ClinicalTrials.gov NCT05142306

Updated Oct 3, 2026. Something wrong or missing? Report it on the EBS page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z