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Ad4-PA-1

Vaccine (Adenoviral vector) · Immune activation, directed at anthrax PA · developed by Emergent BioSolutions

Phase 1 Most advanced trial (none active)

EBS Developer

1 Registered trials

What is Ad4-PA-1?

Ad4-PA-1 is an adenovirus serotype 4 vector vaccine encoding anthrax protective antigen (PA). It is administered as a primary immunization followed by an AVA boost, studied for prevention of anthrax infection.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Vaccine (Adenoviral vector)
Targets: anthrax PA (antigen)
Mechanism: Immune activation, directed at anthrax PA
Therapy area: Infectious disease
Developer: Emergent BioSolutions (EBS)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT01979406	Phase 1	Anthrax Infection	Completed	EBS

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Anthrax Infection

More from Emergent BioSolutions

AIGIV FDA approved Bacillus anthracis strain V770-NP1-R antigens FDA approved Brincidofovir FDA approved smallpox vaccine live, New York City Board of Health vaccinia strain FDA approved Vaccinia Immune Globulin FDA approved Ad4-EnvC150 Phase 1 Ad4-H5-Vtn Phase 1 Ad4-mgag Phase 1 Ad4-PA-GPI-1 Phase 1 AIDSVAX B/E Phase 1 AV7909 Phase 3 Botulinum Antitoxin Heptavalent Phase 1

Sources

ClinicalTrials.gov NCT01979406

Updated Oct 3, 2026. Something wrong or missing? Report it on the EBS page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z