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AIDSVAX B/E

Vaccine (Peptide vaccine) · Immune activation, directed at HIV gp120 glycoprotein subtype B (MN) and HIV gp120 glycoprotein subtype E (A244) · developed by Emergent BioSolutions

Phase 1 Most advanced trial (none active)

EBS Developer

1 Registered trials

What is AIDSVAX B/E?

AIDSVAX B/E is a vaccine containing HIV gp120 glycoproteins from subtypes B and E adsorbed onto aluminum hydroxide adjuvant, administered intramuscularly. It is designed to elicit immune responses against HIV.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Vaccine (Peptide vaccine)
Targets: HIV gp120 glycoprotein subtype B (MN) (antigen), HIV gp120 glycoprotein subtype E (A244) (antigen)
Mechanism: Immune activation, directed at HIV gp120 glycoprotein subtype B (MN) and HIV gp120 glycoprotein subtype E (A244)
Therapy area: Infectious disease
Developer: Emergent BioSolutions (EBS)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT02771730	Phase 1	Healthy Volunteer	Terminated	EBS

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Healthy VolunteerHIV Vaccine

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Sources

ClinicalTrials.gov NCT02771730

Updated Oct 3, 2026. Something wrong or missing? Report it on the EBS page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z