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Ad4-H5-Vtn

Vaccine (Adenoviral vector) · Immune activation, directed at H5N1 influenza hemagglutinin (HA) · developed by Emergent BioSolutions

Phase 1 Most advanced trial (none active)

EBS Developer

1 Registered trials

What is Ad4-H5-Vtn?

Ad4-H5-Vtn is a live, replication-competent adenovirus serotype 4 vaccine expressing the hemagglutinin antigen of H5N1 influenza. Administered orally in an enteric capsule, it is designed to induce immune responses against avian influenza.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Vaccine (Adenoviral vector)
Targets: H5N1 influenza hemagglutinin (HA) (antigen)
Mechanism: Immune activation, directed at H5N1 influenza hemagglutinin (HA)
Pathways: immune_activation
Therapy area: Infectious disease
Developer: Emergent BioSolutions (EBS)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT01006798	Phase 1	Bird Flu	Completed	EBS

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Bird FluInfluenza

More from Emergent BioSolutions

AIGIV FDA approved Bacillus anthracis strain V770-NP1-R antigens FDA approved Brincidofovir FDA approved smallpox vaccine live, New York City Board of Health vaccinia strain FDA approved Vaccinia Immune Globulin FDA approved Ad4-EnvC150 Phase 1 Ad4-mgag Phase 1 Ad4-PA-1 Phase 1 Ad4-PA-GPI-1 Phase 1 AIDSVAX B/E Phase 1 AV7909 Phase 3 Botulinum Antitoxin Heptavalent Phase 1

Sources

ClinicalTrials.gov NCT01006798

Updated Oct 3, 2026. Something wrong or missing? Report it on the EBS page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z