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NVX-CoV2372

Vaccine (Recombinant protein vaccine) · Immune activation, directed at SARS-CoV-2 spike protein · developed by NOVAVAX

Phase 2 Most advanced trial (none active)

NVAX Developer

1 Registered trials

What is NVX-CoV2372?

NVX-CoV2372 is a protein subunit vaccine against SARS-CoV-2 that contains recombinant spike protein antigen. It is studied as a booster vaccine for COVID-19, including in immunosuppressed populations.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Vaccine (Recombinant protein vaccine)
Targets: SARS-CoV-2 spike protein (antigen)
Mechanism: Immune activation, directed at SARS-CoV-2 spike protein
Pathways: immune_activation
Therapy area: Infectious disease
Developer: NOVAVAX (NVAX)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 2

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT06027229	Phase 2	Immunosuppression	Completed	NVAX

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

COVID-19Immunosuppression

More from NOVAVAX

CIC Vaccine Phase 3 EBOV GP Vaccine Phase 1 Fluzone HD Phase 2/3 ICC Vaccine Phase 1/2 NanoFlu Phase 3 NVX-CoV2373 Phase 3 NVX-CoV2515 Phase 3 NVX-CoV2540 Phase 3 NVX-CoV2601 Phase 2/3 NVX-CoV2705 Phase 3 qNIV Vaccine Phase 2 SARS-CoV-2 rS Phase 1/2

Sources

ClinicalTrials.gov NCT06027229

Updated Oct 3, 2026. Something wrong or missing? Report it on the NVAX page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z