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CIC Vaccine

Vaccine (Recombinant protein vaccine) · Immune activation, directed at SARS-CoV-2 spike protein, influenza A hemagglutinin (H1N1) and influenza A hemagglutinin (H3N2) · developed by Novavax

Phase 3 Most advanced trial (none active)

NVAX Developer

3 Registered trials

What is CIC Vaccine?

CIC Vaccine is a coformulated vaccine containing SARS-CoV-2 spike protein and trivalent influenza hemagglutinin nanoparticle antigens with Matrix-M adjuvant, administered intramuscularly. It is studied for prevention of COVID-19 and influenza.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Vaccine (Recombinant protein vaccine)
Targets: SARS-CoV-2 spike protein (antigen), influenza A hemagglutinin (H1N1) (antigen), influenza A hemagglutinin (H3N2) (antigen), influenza B hemagglutinin (Victoria lineage) (antigen)
Mechanism: Immune activation, directed at SARS-CoV-2 spike protein, influenza A hemagglutinin (H1N1) and influenza A hemagglutinin (H3N2)
Pathways: immune_activation
Therapy area: Infectious disease
Developer: Novavax (NVAX)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 3

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT06482359	Phase 2/3	COVID-19	Withdrawn	NVAX
NCT06291857	Phase 3	COVID-19	Completed	NVAX
NCT05519839	Phase 2	COVID-19	Completed	NVAX

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

COVID-19Influenza

More from Novavax

EBOV GP Vaccine Phase 1 Fluzone HD Phase 2/3 ICC Vaccine Phase 1/2 NanoFlu Phase 3 NVX-CoV2372 Phase 2 NVX-CoV2373 Phase 3 NVX-CoV2515 Phase 3 NVX-CoV2540 Phase 3 NVX-CoV2601 Phase 2/3 NVX-CoV2705 Phase 3 qNIV Vaccine Phase 2 SARS-CoV-2 rS Phase 1/2

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the NVAX page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z