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NBI-921352 · XEN-901

Small molecule · developed by NEUROCRINE BIOSCIENCES

Phase 2 Most advanced trial (none active)
NBIX Developer
1 Registered trials

What is NBI-921352?

NBI-921352 is a small-molecule inhibitor of the sodium channel Nav1.6, encoded by SCN8A. It is being studied for the treatment of SCN8A developmental and epileptic encephalopathy syndrome, a severe neurological disorder caused by mutations in the SCN8A gene.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
XEN-901
Drug type
Small molecule
Therapy area
Neurology
Developer
NEUROCRINE BIOSCIENCES (NBIX)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 2
UNII
SV2WPA4R4J

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT05226780 Phase 2 SCN8A Developmental and Epileptic Encephalopathy Syndrome Terminated NBIX

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

SCN8A Developmental and Epileptic Encephalopathy Syndrome

More from NEUROCRINE BIOSCIENCES

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

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