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Elebsiran · VIR-2218

Oligonucleotide (siRNA) · Gene silencing · developed by ALNYLAM PHARMACEUTICALS

Phase 2 Most advanced trial (none active)

ALNY Developer

1 Registered trials

What is Elebsiran?

Elebsiran (VIR-2218, ALN-81890) is a small interfering RNA given by subcutaneous injection.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as: VIR-2218
Drug type: Oligonucleotide (siRNA)
Mechanism: Gene silencing
Therapy area: Infectious disease
Developer: ALNYLAM PHARMACEUTICALS (ALNY)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 2
UNII: W982Y6N4X7

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT04412863	Phase 2	Chronic Hepatitis B	Completed	ALNY

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Chronic Hepatitis B

More from ALNYLAM PHARMACEUTICALS

Givosiran FDA approved Lumasiran FDA approved Patisiran FDA approved Vutrisiran FDA approved ALN-2232 Phase 1/2 ALN-4285 Phase 1 ALN-4324 Phase 2 ALN-4915 Phase 1 ALN-5288 Phase 1 ALN-6222 Phase 1 ALN-6400 Phase 1/2 ALN-AGT01 RVR Phase 2

Sources

ClinicalTrials.gov NCT04412863

Updated Oct 11, 2026. Something wrong or missing? Report it on the ALNY page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z