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Camoteskimab · AEVI-007, AVTX-007

Monoclonal antibody · Antagonist of interleukin-18 (IL18) · developed by Avalo Therapeutics

Phase 1 Most advanced trial (none active)
AVTX Developer
1 Registered trials

What is Camoteskimab?

Camoteskimab is a human IgG1 monoclonal antibody that binds interleukin-18 (IL-18), a member of the IL-1 cytokine superfamily, and inhibits IL-18-mediated signaling and inflammation. It is being studied in multiple myeloma, where elevated IL-18 is associated with disease progression.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
AEVI-007, AVTX-007
Drug type
Monoclonal antibody
Targets
interleukin-18 (IL18)
Mechanism
Antagonist of interleukin-18 (IL18)
Pathways
IL-18 signaling, inflammation, IL-18-mediated immunosuppression in the multiple myeloma microenvironment
Therapy area
Oncology
Developer
Avalo Therapeutics, Inc. (AVTX)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 1
UNII
ONX021SC9O

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT04671251 Phase 1 Multiple Myeloma Completed AVTX

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Multiple Myeloma

More from Avalo Therapeutics

Sources

Updated Oct 11, 2026. Something wrong or missing? Report it on the AVTX page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

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