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AT-777

Small molecule · Inhibitor of HCV nonstructural protein 5A (NS5A) · developed by Atea Pharmaceuticals

Phase 1/2 Most advanced trial (none active)
AVIR Developer
1 Registered trials

What is AT-777?

AT-777 is an oral inhibitor of the hepatitis C virus nonstructural protein 5A (NS5A), supplied as 60 mg capsules. It is studied in chronic hepatitis C virus infection.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type
Small molecule
Targets
HCV nonstructural protein 5A (NS5A)
Mechanism
Inhibitor of HCV nonstructural protein 5A (NS5A)
Therapy area
Infectious disease
Developer
Atea Pharmaceuticals, Inc. (AVIR)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 1/2

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT04309734 Phase 1/2 Hepatitis C Withdrawn AVIR

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Chronic Hepatitis CHCV InfectionHepatitis CHepatitis C Virus InfectionHepatitis C, Chronic

More from Atea Pharmaceuticals

AT-527 Phase 1 AT-587 Phase 1 AT-752 Phase 2 Bemnifosbuvir Phase 3 Bemnifosbuvir-Ruzasvir Phase 3 Ethinyl Estradioll/Levonorgestrel Phase 1 Ruzasvir Phase 2 Treatment A-Bemnifosbuvir/Ruzasvir FDC Phase 1

Sources

Updated Oct 11, 2026. Something wrong or missing? Report it on the AVIR page.

Follow AVIR, the company behind AT-777

See AVIR's upcoming FDA decisions, trial readouts, cash runway and dilution risk, updated every day from SEC, FDA and ClinicalTrials.gov filings.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.