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VX-828

Small molecule · developed by VERTEX PHARMACEUTICALS INC / MA

Phase 1 Most advanced trial (none active)

VRTX Developer

1 Registered trials

What is VX-828?

VX-828 is an investigational small-molecule drug studied in Cystic Fibrosis.

At a glance

Drug type: Small molecule
Therapy area: Respiratory
Developer: VERTEX PHARMACEUTICALS INC / MA (VRTX)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT06154447	Phase 1	Cystic Fibrosis	Completed	VRTX

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Cystic Fibrosis

More from VERTEX PHARMACEUTICALS INC / MA

Deutivacaftor FDA approved Elexacaftor FDA approved Exagamglogene Autotemcel FDA approved Ivacaftor FDA approved Suzetrigine FDA approved Tezacaftor FDA approved Vanzacaftor FDA approved Inaxaplin Phase 2/3 Povetacicept Phase 2/3 VX-017 Phase 3 VX-118 Phase 1 VX-264 Phase 1/2

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the VRTX page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z