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VLA84

Vaccine (Recombinant protein vaccine) · Immune activation, directed at Clostridium difficile toxin A and Clostridium difficile toxin B · developed by Valneva Austria GmbH

Phase 2 Most advanced trial (none active)

VALN Developer

1 Registered trials

What is VLA84?

VLA84 is a recombinant fusion protein made of truncated Clostridium difficile Toxin A and Toxin B. It is studied in Clostridium difficile infection.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Vaccine (Recombinant protein vaccine)
Targets: Clostridium difficile toxin A (antigen), Clostridium difficile toxin B (antigen)
Mechanism: Immune activation, directed at Clostridium difficile toxin A and Clostridium difficile toxin B
Therapy area: Infectious disease
Developer: Valneva Austria GmbH (VALN)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 2

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT02316470	Phase 2	Clostridium Difficile	Completed	VALN

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Clostridium Difficile

More from Valneva Austria GmbH

IC51 FDA approved Japanese encephalitis virus vaccine, inactivated FDA approved 3M-052-AF Phase 1 ChAdOx1 nCoV-19 Vaccine Phase 3 IC41 Phase 2 IC43 Phase 2/3 IC47 Phase 1 IC84 Phase 1 ISS 1018 CpG Oligodeoxynucleotide Phase 1 JE-VAX Phase 3 Pneumococcal 7-Valent Conjugate Vaccine Phase 3 VLA1553 Phase 3

Sources

ClinicalTrials.gov NCT02316470

Updated Oct 11, 2026. Something wrong or missing? Report it on the VALN page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z