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VGX-3400X

Vaccine (DNA plasmid) · Immune activation, directed at avian influenza virus antigens · developed by Inovio Pharmaceuticals

Phase 1 Most advanced trial (none active)

INO Developer

1 Registered trials

What is VGX-3400X?

VGX-3400X is a DNA plasmid vaccine delivered via intramuscular injection with electroporation using the CELLECTRA device. It is designed to elicit immune responses against avian influenza virus antigens.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Vaccine (DNA plasmid)
Targets: avian influenza virus antigens (antigen)
Mechanism: Immune activation, directed at avian influenza virus antigens
Therapy area: Infectious disease
Developer: Inovio Pharmaceuticals (INO)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT01142362	Phase 1	Healthy	Completed	INO

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Healthy

More from Inovio Pharmaceuticals

DNA Plasmid-encoding Interleukin-12 INO-9012/PSA/PSMA DNA Plasmids INO-5150 Phase 1 INO-1400 Phase 1 INO-1401 Phase 1 INO-1800 Phase 1 INO-3106 Phase 1 INO-3107 Phase 1/2 INO-3401 Phase 1 INO-4201 Phase 1 INO-4202 Phase 1 INO-4212 Phase 1 INO-4500 Phase 1 INO-4700 Phase 2

Sources

ClinicalTrials.gov NCT01142362

Updated Oct 3, 2026. Something wrong or missing? Report it on the INO page.

Follow INO, the company behind VGX-3400X

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z