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Vebicorvir · VBR

Small molecule · Inhibitor of hepatitis B virus core protein · developed by Assembly Biosciences

Phase 2 Most advanced trial (none active)
ASMB Developer
3 Registered trials

What is Vebicorvir?

Vebicorvir (VBR) is an oral tablet that inhibits the hepatitis B virus core protein. It is studied in chronic hepatitis B, given as 300 mg once daily.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
VBR, ABI-H0731
Drug type
Small molecule
Targets
hepatitis B virus core protein
Mechanism
Inhibitor of hepatitis B virus core protein
Therapy area
Infectious disease
Developer
Assembly Biosciences (ASMB)
Also in trials of
ABUS
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 2
UNII
16F6055SMG

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT04820686 Phase 2 Chronic Hepatitis B Terminated ABUS
NCT04781647 Phase 2 Chronic Hepatitis B Terminated ASMB
NCT04637139 Phase 1 Chronic Hepatitis B Completed ASMB

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Chronic Hepatitis B

More from Assembly Biosciences

Sources

Updated Oct 11, 2026. Something wrong or missing? Report it on the ASMB page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

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