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VCAR33

Cell therapy (CAR-T) · Kills target cells, directed at CD33 · developed by Vor Biopharma

Phase 1/2 Most advanced trial (none active)
VOR Developer
1 Registered trials

What is VCAR33?

VCAR33 is an allogeneic CAR T-cell therapy derived from matched healthy donor stem cell transplant recipients and engineered to express a chimeric antigen receptor targeting CD33. It is designed to recognize and kill CD33-expressing myeloid leukemia cells and is being studied in acute myeloid leukemia.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type
Cell therapy (CAR-T)
Targets
CD33 (antigen)
Mechanism
Kills target cells, directed at CD33
Therapy area
Oncology
Developer
Vor Biopharma (VOR)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 1/2

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT05984199 Phase 1/2 Leukemia, Myeloid, Acute Terminated VOR

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Leukemia, Myeloid, Acute

Other drugs acting on CD33

More from Vor Biopharma

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the VOR page.

Follow VOR, the company behind VCAR33

See VOR's upcoming FDA decisions, trial readouts, cash runway and dilution risk, updated every day from SEC, FDA and ClinicalTrials.gov filings.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.