Testosterone · Testim, Testoderm Tts

What is Testosterone?

Testosterone is an endogenous androgen that is used as a topical gel for testosterone replacement therapy in adult males. It acts on androgen receptors to maintain male sex characteristics.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as

Testim, Testoderm Tts, Vogelxo

Drug type

Small molecule

Targets

androgen receptor (AR)

Mechanism

Agonist of androgen receptor (AR)

Therapy area

Endocrine

Developer

Alza

In trials of

AMRX

FDA status

Approved as Testim, Testoderm Tts, Vogelxo (December 18, 1997), NDA020791 · FDA label

✅ FDA-approved uses

• Primary hypogonadism (Testim)
• Hypogonadotropic hypogonadism (Testim)
• Primary hypogonadism (Vogelxo)
• Hypogonadotropic hypogonadism (Vogelxo)

From the indications section of the FDA label (version of Jul 15, 2025). Read the full label for the exact wording, limitations and safety information.

🧪 Clinical trials

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Hypogonadotropic HypogonadismPrimary Hypogonadism

Other drugs acting on AR

Sources

• FDA label (DailyMed)
• FDA label Testim (2025-07-15), indications
• FDA label Vogelxo (2025-07-14), indications
• FDA label Testosterone (2024-09-30), indications

Updated Oct 11, 2026.