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Tabelecleucel · ATA-129, ATA188

Cell therapy (Antigen-specific T cells) · Kills target cells, directed at Epstein-Barr virus-associated antigens · developed by Atara Biotherapeutics

Phase 1/2 Most advanced trial (none active)
ATRA Developer
3 Registered trials

What is Tabelecleucel?

Tabelecleucel is an allogeneic, off-the-shelf cytotoxic T-lymphocyte therapy directed against Epstein-Barr virus (EBV) antigens expressed on EBV-infected cells. It binds these antigens and lyses the infected cells. It is studied in EBV-associated lymphomas and malignancies, EBV-associated nasopharyngeal carcinoma, and EBV-positive progressive multiple sclerosis.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
ATA-129, ATA188, tab-cel, EBV-CTLs
Drug type
Cell therapy (Antigen-specific T cells)
Targets
Epstein-Barr virus-associated antigens (antigen)
Mechanism
Kills target cells, directed at Epstein-Barr virus-associated antigens
Therapy area
Immunology, Oncology
Developer
Atara Biotherapeutics (ATRA)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 1/2
UNII
G3NJ7M8N4H

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT03769467 Phase 1/2 Nasopharyngeal Carcinoma Terminated ATRA
NCT03283826 Phase 1/2 Primary Progressive Multiple Sclerosis Terminated ATRA
NCT01498484 Phase 2 EBV-induced Lymphomas Completed ATRA

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

EBV-associated MalignanciesEBV-induced LymphomasEpstein-Barr ViraemiaEpstein-Barr Virus InfectionsNasopharyngeal CarcinomaNasopharyngeal NeoplasmsPrimary Progressive Multiple SclerosisSecondary Progressive Multiple Sclerosis

More from Atara Biotherapeutics

Sources

Updated Oct 11, 2026. Something wrong or missing? Report it on the ATRA page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.