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Pritelivir · AIC-316, AIC-090093

Small molecule · Inhibitor of herpes simplex virus helicase-primase complex · developed by AiCuris Anti-infective Cures

Phase 3 Most advanced trial (none active)
2 Registered trials

What is Pritelivir?

Pritelivir is a thiazolylamide small-molecule inhibitor of the herpes simplex virus helicase-primase complex. It prevents viral DNA replication by blocking helicase and primase catalytic cycling, and does not require HSV thymidine kinase activation. It is studied in genital herpes and HSV infection.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
AIC-316, AIC-090093
Drug type
Small molecule
Targets
herpes simplex virus helicase-primase complex
Mechanism
Inhibitor of herpes simplex virus helicase-primase complex
Pathways
viral DNA replication
Therapy area
Infectious disease
Developer
AiCuris Anti-infective Cures AG
In trials of
MEDP
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 3
UNII
07HQ1TJ4JE

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT03073967 Phase 3 HSV Infection Completed MEDP
NCT01658826 Phase 2 Genital Herpes Terminated MEDP

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Genital HerpesHSV Infection

Sources

Updated Oct 3, 2026.

Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.