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Leukocyte Interleukin · LI

Recombinant protein · Immune activation · developed by CEL-SCI

Phase 3 Most advanced trial (none active)
CVM Developer
3 Registered trials

What is Leukocyte Interleukin?

Leukocyte Interleukin (Multikine) is a cocktail of synthetic cytokines including IL-1, IL-2, IL-6, TNF-alpha, and interferon gamma. It activates immune responses including antibody production and cytokine modulation. It is studied in squamous cell carcinoma of the head and neck and condyloma as neoadjuvant therapy.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
LI, Multikine
Drug type
Recombinant protein
Mechanism
Immune activation
Pathways
immune_activation, cytokine signaling
Therapy area
Infectious disease, Oncology
Developer
CEL-SCI Corporation (CVM)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 3

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT01265849 Phase 3 Squamous Cell Carcinoma of the Oral Cavity Completed CVM
NCT03038828 Phase 1 Perianal Warts Terminated CVM
NCT02115919 Phase 1 Condyloma Terminated CVM

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

CondylomaPerianal WartsSquamous Cell Carcinoma of the Oral CavitySquamous Cell Carcinoma of the Soft Palate

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the CVM page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.