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Lasmecabtagene Timgedleucel · UCART-22

Cell therapy (CAR-T) · Kills target cells, directed at CD22 · developed by Cellectis

Phase 1/2 Most advanced trial
CLLS Developer
1 Registered trials

What is Lasmecabtagene Timgedleucel?

Lasmecabtagene timgedleucel is an allogeneic, off-the-shelf T-lymphocyte cell therapy engineered with TALEN gene editing to express a chimeric antigen receptor targeting CD22. The CAR-expressing cells bind CD22 on tumor cells, leading to lysis of CD22-expressing cells. It is being studied in B-cell acute lymphoblastic leukemia.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
UCART-22
Drug type
Cell therapy (CAR-T)
Targets
CD22 (antigen)
Mechanism
Kills target cells, directed at CD22
Therapy area
Oncology
Developer
Cellectis S.A. (CLLS)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 1/2
UNII
5GP3N2YX96

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT04150497 Phase 1/2 B-cell Acute Lymphoblastic Leukemia Recruiting CLLS

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

B-cell Acute Lymphoblastic Leukemia

Other drugs acting on CD22

More from Cellectis

Sources

Updated Oct 11, 2026. Something wrong or missing? Report it on the CLLS page.

Follow CLLS, the company behind Lasmecabtagene Timgedleucel

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

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