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IONIS-FB-LRx · ISIS-696844

Oligonucleotide (Antisense oligonucleotide) · developed by IONIS PHARMACEUTICALS

Phase 2 Most advanced trial (none active)

IONS Developer

1 Registered trials

What is IONIS-FB-LRx?

IONIS-FB-LRx is an investigational oligonucleotide studied in Macular Degeneration, Geographic Atrophy.

At a glance

Also known as: ISIS-696844
Drug type: Oligonucleotide (Antisense oligonucleotide)
Therapy area: Ophthalmology
Developer: IONIS PHARMACEUTICALS (IONS)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 2
UNII: 37KI8XF3IH

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT03815825	Phase 2	Macular Degeneration	Completed	IONS

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Geographic AtrophyMacular Degeneration

More from IONIS PHARMACEUTICALS

Donidalorsen FDA approved Olezarsen FDA approved Zilganersen FDA approved BIIB094 Phase 1 ION224 Phase 2 ION269 Phase 1 ION337 Phase 1/2 ION356 Phase 1 ION363 Phase 3 ION440 Phase 1/2 ION464 Phase 1 ION717 Phase 1/2

Sources

ClinicalTrials.gov NCT03815825

Updated Oct 3, 2026. Something wrong or missing? Report it on the IONS page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z