Dashboard PDUFA PDUFA History Dilution Watch Downside Radar Missed Milestones Earnings Big Movers Blog

🎤 Upcoming Biotech Conferences

Loading conferences...
Free to browse, no account needed Follow the companies behind these drugs with free AI briefings, catalyst countdowns and dilution alerts.
Start 7-day free trial → Log in

HER-2/neu Peptide Vaccine

Vaccine (Peptide vaccine) · Immune activation, directed at HER2 (ERBB2)

Phase 1 Most advanced trial (none active)
1 Registered trials

What is HER-2/neu Peptide Vaccine?

HER-2/neu peptide vaccine is a cancer vaccine comprised of peptides derived from the extracellular domain of HER2. It is designed to induce antibodies and CD8 T-cell responses against HER2-positive tumor cells. The vaccine is studied in HER2-positive breast cancer, including male breast cancer and stage II-IIIC disease.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
HER-2
Drug type
Vaccine (Peptide vaccine)
Targets
HER2 (ERBB2) (antigen)
Mechanism
Immune activation, directed at HER2 (ERBB2)
Pathways
immune_activation
Therapy area
Oncology
In trials of
MRKR
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT01632332 Phase 1 HER2-positive Breast Cancer Completed MRKR

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

HER2-positive Breast CancerMale Breast CancerStage II Breast CancerStage IIIA Breast CancerStage IIIB Breast CancerStage IIIC Breast Cancer

Other drugs acting on ERBB2

Neratinib FDA approved Trastuzumab Deruxtecan FDA approved Trastuzumab Emtansine FDA approved Zanidatamab FDA approved ADCT-502 Phase 1 BH-30643 Phase 1/2 CGT4255 Phase 1 CUDC-101 Phase 1 ELVN-002 Phase 1 Enozertinib Phase 1/2 NVL-330 Phase 1 TTX-MC138 Phase 1/2

Sources

Updated Oct 3, 2026.

Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.