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Glycopyrronium · Qbrexza

Small molecule · Antagonist of acetylcholine receptor · developed by Journey

Approved FDA, Jun 2018
DERM Developer
3 Registered trials

What is Glycopyrronium?

Glycopyrronium is a competitive antagonist of acetylcholine receptors on sweat glands. Applied topically as wipes or cloth, it reduces sweating in primary axillary hyperhidrosis.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
Qbrexza
Drug type
Small molecule
Targets
acetylcholine receptor
Mechanism
Antagonist of acetylcholine receptor
Therapy area
Dermatology
Developer
Journey (DERM)
FDA status
Approved as Qbrexza (June 28, 2018), NDA210361 · FDA label

✅ FDA-approved uses

From the indications section of the FDA label (version of May 21, 2026). Read the full label for the exact wording, limitations and safety information.

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT02553798 Phase 3 Hyperhidrosis Completed DERM
NCT03880266 Phase 2 Palmar Hyperhidrosis Completed DERM
NCT02129660 Phase 2 Hyperhidrosis Completed DERM

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

HyperhidrosisPalmar Hyperhidrosis

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the DERM page.

Follow DERM, the company behind Glycopyrronium

See DERM's upcoming FDA decisions, trial readouts, cash runway and dilution risk, updated every day from SEC, FDA and ClinicalTrials.gov filings.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.