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Galinpepimut-S · SLS-001, GPS

Vaccine (Peptide vaccine) · Immune activation, directed at WT1 · developed by Sellas Life Sciences Group

Phase 3 Most advanced trial
SLS Developer
2 Registered trials

What is Galinpepimut-S?

Galinpepimut-S is a peptide cancer vaccine comprised of four WT1-derived peptide chains designed to elicit CD4-positive and CD8-positive T-cell responses against WT1-expressing tumor cells. It is studied in acute myeloid leukemia and malignant pleural mesothelioma.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
SLS-001, GPS
Drug type
Vaccine (Peptide vaccine)
Targets
WT1 (antigen)
Mechanism
Immune activation, directed at WT1
Pathways
immune_activation
Therapy area
Oncology
Developer
Sellas Life Sciences Group (SLS)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 3
UNII
12R66419FZ

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT04229979 Phase 3 Acute Myeloid Leukemia Active not recruiting SLS
NCT01265433 Phase 2 Malignant Pleural Mesothelioma Completed SLS

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Acute Myeloid LeukemiaMalignant Pleural Mesothelioma

More from Sellas Life Sciences Group

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the SLS page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

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