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Ethinyl Estradiol/Levonorgestrel · Levonorgestrel And Ethinyl Estradiol

Small molecule · Acts on estrogen receptor (ESR1) and progesterone receptor (PGR) · developed by Acella Pharmaceuticals

Approved FDA
1 Registered trials

What is Ethinyl Estradiol/Levonorgestrel?

Ethinyl estradiol and levonorgestrel are a combined oral contraceptive pairing a synthetic estrogen with a synthetic progestogen. The combination is used for contraception.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
Levonorgestrel And Ethinyl Estradiol
Drug type
Small molecule
Targets
estrogen receptor (ESR1), progesterone receptor (PGR)
Mechanism
Acts on estrogen receptor (ESR1) and progesterone receptor (PGR)
Pathways
ovulation suppression, endometrial alteration, cervical mucus changes
Therapy area
Gastroenterology, Infectious disease
Developer
Acella Pharmaceuticals
In trials of
ASMB
FDA status
Approved as Levonorgestrel And Ethinyl Estradiol, NDA208612 · FDA label

✅ FDA-approved uses

From the indications section of the FDA label (version of Dec 5, 2025). Read the full label for the exact wording, limitations and safety information.

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT04142762 Phase 1 Chronic Hepatitis B Completed ASMB

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Chronic Hepatitis B

Other drugs acting on ESR1 / PGR

Camizestrant FDA approved Imlunestrant FDA approved Mifepristone FDA approved Segesterone Acetate and Ethinyl Estradiol FDA approved Tamoxifen FDA approved Vepdegestrant FDA approved Giredestrant Phase 1/2 Onapristone Phase 1/2 Zuclomiphene Phase 2

Sources

Updated Oct 11, 2026.

Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.