Ethambutol · Ethambutol Hydrochloride

What is Ethambutol?

Ethambutol is a small-molecule antibiotic that inhibits arabinosyl transferases, blocking the biosynthesis of arabinogalactan in the mycobacterial cell wall.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as

Ethambutol Hydrochloride

Drug type

Small molecule

Targets

arabinosyl transferases

Mechanism

Inhibitor of arabinosyl transferases

Pathways

arabinogalactan biosynthesis, cell wall synthesis

Therapy area

Infectious disease

Developer

Kanchan Hlthcare

In trials of

INVA, SPRO

FDA status

Approved as Ethambutol Hydrochloride (November 6, 1967), NDA016320 · FDA label

UNII

8G167061QZ

✅ FDA-approved uses

• Pulmonary tuberculosis

From the indications section of the FDA label (version of May 5, 2026). Read the full label for the exact wording, limitations and safety information.

🧪 Clinical trials

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Mycobacterium Abscessus InfectionMycobacterium Abscessus Pulmonary DiseaseNon-Tuberculous Mycobacteria Pulmonary DiseaseNon-Tuberculous Mycobacterial (NTM) InfectionsHealthy Volunteers

Sources

• FDA label Ethambutol Hydrochloride (2026-05-05), indications
• NCI Thesaurus
• ClinicalTrials.gov NCT05966688
• ClinicalTrials.gov NCT07485010

Updated Oct 3, 2026.