Diazepam · Valtoco

What is Diazepam?

Diazepam is a benzodiazepine that binds the benzodiazepine site of the GABA-A receptor, potentiating GABAergic neurotransmission. It is studied in epilepsy, including buccal film and rectal gel formulations.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as

Valtoco

Drug type

Small molecule

Targets

GABA-A receptor

Mechanism

Modulator of GABA-A receptor

Pathways

GABAergic neurotransmission

Therapy area

Neurology

Developer

Neurelis, Inc

In trials of

AQST

FDA status

Approved as Valtoco, NDA211635 · FDA label

UNII

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✅ FDA-approved uses

• Seizure clusters (acute repetitive seizures) in patients with epilepsy 2 years of age and older

From the indications section of the FDA label (version of Jun 3, 2026). Read the full label for the exact wording, limitations and safety information.

🧪 Clinical trials

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Epilepsy

Sources

• FDA label (DailyMed)
• FDA label Valtoco (2026-06-03), indications
• ClinicalTrials.gov NCT03179891
• ClinicalTrials.gov NCT03222349
• ClinicalTrials.gov NCT03953820
• ClinicalTrials.gov NCT03953820

Updated Oct 11, 2026.