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Descartes-15

Cell therapy (CAR-T) · Kills target cells, directed at BCMA (TNFRSF17) · developed by Cartesian Therapeutics

Phase 1 Most advanced trial (none active)

RNAC Developer

1 Registered trials

What is Descartes-15?

Descartes-15 is an autologous CAR-T cell therapy directed against BCMA. It is being studied in patients with refractory or relapsed multiple myeloma.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type: Cell therapy (CAR-T)
Targets: BCMA (TNFRSF17) (antigen)
Mechanism: Kills target cells, directed at BCMA (TNFRSF17)
Therapy area: Oncology
Developer: Cartesian Therapeutics (RNAC)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT06304636	Phase 1	Refractory Multiple Myeloma	Terminated	RNAC

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Refractory Multiple MyelomaRelapsed Multiple Myeloma

Other drugs acting on TNFRSF17

SEA-BCMA Phase 1

More from Cartesian Therapeutics

Descartes 30 Phase 1 Descartes-08 Phase 3 Descartes-11 Phase 2 Descartes-25 Phase 1

Sources

ClinicalTrials.gov NCT06304636

Updated Oct 3, 2026. Something wrong or missing? Report it on the RNAC page.

Follow RNAC, the company behind Descartes-15

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z