Oncolytic virus (Adenoviral vector) · Kills target cells · developed by CG Oncology
Phase 2Most advanced trial (none active)
1Registered trials
What is Cretostimogene Grenadenorepvec?
Cretostimogene grenadenorepvec is a recombinant oncolytic adenovirus that selectively infects and replicates in tumor cells, causing their lysis. It encodes granulocyte-macrophage colony-stimulating factor (GM-CSF), which may promote a cytotoxic T cell response against tumor cells. It is studied in non-muscle invasive bladder cancer.
Summary written with AI from the sources listed at the end of this page.
At a glance
Also known as
CG-0070
Drug type
Oncolytic virus (Adenoviral vector)
Mechanism
Kills target cells
Pathways
cytotoxic T cell response, immune-mediated tumor cell death
Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z
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