Clindamycin · Cleocin Phosphate, Xaciato

What is Clindamycin?

Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to the 23S RNA of the bacterial ribosome's 50S subunit.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as

Cleocin Phosphate, Xaciato

Drug type

Small molecule

Targets

bacterial 23S rRNA

Mechanism

Inhibitor of bacterial 23S rRNA

Pathways

bacterial protein synthesis

Therapy area

Dermatology

Developer

Pfizer

In trials of

BHC

FDA status

Approved as Cleocin Phosphate, Xaciato (August 30, 1989), NDA050639 · FDA label

✅ FDA-approved uses

• Serious infections caused by susceptible anaerobic bacteria (Cleocin Phosphate)
• Serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci (Cleocin Phosphate)
• Bacterial vaginosis (Xaciato)

From the indications section of the FDA label (version of Jul 29, 2026). Read the full label for the exact wording, limitations and safety information.

🧪 Clinical trials

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Acne

Sources

• FDA label (DailyMed)
• FDA label Cleocin Phosphate (2026-07-29), indications
• FDA label Xaciato (2026-02-19), indications
• NCI Thesaurus

Updated Oct 3, 2026.