Small molecule · Cytotoxic, directed at genomic DNA · developed by Hq Spclt Pharma
ApprovedFDA, Dec 1978
1Registered trials
What is Cisplatin?
Cisplatin is a platinum-based small molecule that binds to genomic DNA to form interstrand and intrastrand cross-links, interfering with transcription and DNA replication and triggering cell death.
Summary written with AI from the sources listed at the end of this page.
At a glance
Drug type
Small molecule
Targets
genomic DNA
Mechanism
Cytotoxic, directed at genomic DNA
Pathways
DNA cross-linking, transcription inhibition, DNA replication inhibition, apoptosis
From the indications section of the FDA label (version of Jun 24, 2026). Read the full label for the exact wording, limitations and safety information.
Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z
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