Ceftriaxone · Ceftriaxone And Dextrose

What is Ceftriaxone?

Ceftriaxone is a third-generation cephalosporin antibiotic that binds to and inactivates penicillin-binding proteins in the bacterial cell wall, disrupting peptidoglycan cross-linkage and causing cell lysis.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as

Ceftriaxone And Dextrose

Drug type

Small molecule

Targets

penicillin-binding proteins

Mechanism

Inhibitor of penicillin-binding proteins

Pathways

bacterial cell wall synthesis

Therapy area

Infectious disease

Developer

B Braun

In trials of

INVA

FDA status

Approved as Ceftriaxone And Dextrose (April 20, 2005), NDA050796 · FDA label

✅ FDA-approved uses

• Lower Respiratory Tract Infections
• Skin and Skin Structure Infections
• Complicated and Uncomplicated Urinary Tract Infections
• Pelvic Inflammatory Disease
• Bacterial Septicemia
• Bone and Joint Infections
• Intra-abdominal Infections
• Meningitis

From the indications section of the FDA label (version of Jan 13, 2022). Read the full label for the exact wording, limitations and safety information.

🧪 Clinical trials

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Mycobacterium Abscessus InfectionMycobacterium Abscessus Pulmonary DiseaseNon-Tuberculous Mycobacteria Pulmonary DiseaseNon-Tuberculous Mycobacterial (NTM) Infections

Sources

• FDA label (DailyMed)
• FDA label Ceftriaxone And Dextrose (2022-01-13), indications
• NCI Thesaurus
• ClinicalTrials.gov NCT07485010

Updated Oct 3, 2026.