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Belapectin

Small molecule · Inhibitor of galectin-3 (LGALS3) · developed by Galectin Therapeutics

Phase 2/3 Most advanced trial (none active)
GALT Developer
3 Registered trials

What is Belapectin?

Belapectin is a carbohydrate-based galectin inhibitor that binds the carbohydrate-binding domain of galectins, especially galectin-3. It is being studied in metastatic melanoma, nonalcoholic steatohepatitis, cirrhosis and prevention of esophageal varices.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
GR-MD-02, galactoarabino rhamnogalacturonate
Drug type
Small molecule
Targets
galectin-3 (LGALS3)
Mechanism
Inhibitor of galectin-3 (LGALS3)
Pathways
apoptosis, tumor angiogenesis, immune evasion
Therapy area
Gastroenterology, Oncology
Developer
Galectin Therapeutics Inc. (GALT)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 2/3
UNII
K7ODU55HT6

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT04365868 Phase 2/3 Prevention of Esophageal Varices Terminated GALT
NCT02421094 Phase 2 Nonalcoholic Steatohepatitis Completed GALT
NCT02117362 Phase 1 Metastatic Melanoma Completed GALT

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

CirrhosisMetastatic MelanomaNASH - Nonalcoholic SteatohepatitisNonalcoholic SteatohepatitisPrevention of Esophageal Varices

More from Galectin Therapeutics

Sources

Updated Oct 11, 2026. Something wrong or missing? Report it on the GALT page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.