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AST-OPC1

Cell therapy (Stem-cell derived) · Cell replacement: spinal cord tissue · developed by Lineage Cell Therapeutics

Phase 1/2 Most advanced trial
LCTX Developer
2 Registered trials

What is AST-OPC1?

AST-OPC1 is a cell therapy consisting of oligodendrocyte progenitor cells derived from embryonic stem cells. It is administered by direct injection into damaged spinal cord tissue and is being studied in acute and chronic spinal cord injury.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
OPC1
Drug type
Cell therapy (Stem-cell derived)
Targets
spinal cord tissue
Mechanism
Cell replacement: spinal cord tissue
Therapy area
Neurology
Developer
Lineage Cell Therapeutics, Inc. (LCTX)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 1/2

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT02302157 Phase 1/2 Cervical Spinal Cord Injury Completed LCTX
NCT06841770 Phase 1 Spinal Cord Injury Cervical Recruiting LCTX

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Spinal Cord InjurySpinal Cord Injury CervicalSpinal Cord Injury ThoracicSpinal Cord Injury, AcuteSpinal Cord Injury, ChronicCervical Spinal Cord InjurySpinal Cord TraumaSpine Injury

More from Lineage Cell Therapeutics

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the LCTX page.

Follow LCTX, the company behind AST-OPC1

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.