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AGEN2017

Vaccine (Peptide vaccine) · Immune activation, directed at neoantigens · developed by Agenus

Phase 1 Most advanced trial (none active)
AGEN Developer
1 Registered trials

What is AGEN2017?

AGEN2017 is a personalized autologous peptide vaccine composed of patient-specific neoantigen peptides complexed with heat shock protein 70 (HSP70). The vaccine elicits neoantigen-specific T-cell responses by presenting neoantigens to antigen-presenting cells, thereby targeting neoantigen-expressing cancer cells. It is studied in solid tumors.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type
Vaccine (Peptide vaccine)
Targets
neoantigens (antigen)
Mechanism
Immune activation, directed at neoantigens
Pathways
T-cell-mediated immune response, antigen presentation
Therapy area
Oncology
Developer
Agenus Inc. (AGEN)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT03673020 Phase 1 Solid Tumor, Adult Completed AGEN

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Solid Tumor, Adult

More from Agenus

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the AGEN page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

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