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ADX-850

Oligonucleotide (siRNA) · Gene silencing · developed by ADARx Pharmaceuticals

Phase 1 Most advanced trial

ADRX Developer

3 Registered trials

What is ADX-850?

ADX-850 is a siRNA duplex oligonucleotide being studied in hypertension.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as: siRNA
Drug type: Oligonucleotide (siRNA)
Mechanism: Gene silencing
Therapy area: Cardiovascular
Developer: ADARx Pharmaceuticals, Inc. (ADRX)
FDA status: Investigational, not approved in the US. Most advanced trial: Phase 1

🧪 Clinical trials

Trial	Phase	Condition	Status	Sponsor
NCT06960213	Phase 3	Hereditary Angioedema	Recruiting	ADRX
NCT05876312	Phase 1/2	Paroxysmal Nocturnal Hemoglobinuria (PNH)	Recruiting	ADRX
NCT06205628	Phase 1	Hypertension	Active not recruiting	ADRX

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

HypertensionHypertension,Essential

More from ADARx Pharmaceuticals

ADX-038 Phase 1/2 ADX-324 Phase 3 ADX-626 Phase 1

Sources

ClinicalTrials.gov NCT06205628

Updated Oct 3, 2026. Something wrong or missing? Report it on the ADRX page.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z