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Acellular Tissue Engineered Vessel · Symvess, ATEV

Other · developed by Humacyte Global

Approved FDA, Dec 2024
HUMA Developer
7 Registered trials

What is Acellular Tissue Engineered Vessel?

Symvess is an acellular tissue engineered vessel composed of human extracellular matrix. It is designed to function as a vascular conduit for arterial repair and can support cell binding and proliferation.

Summary written with AI from the sources listed at the end of this page.

At a glance

Also known as
Symvess, ATEV, HAV, Human Acellular Vessel (HAV), HAV implantation
Drug type
Other
Therapy area
Cardiovascular
Developer
Humacyte Global, Inc. (HUMA)
FDA status
Approved as Symvess (December 19, 2024), BLA125812 · FDA label
UNII
6H248RS8YQ

✅ FDA-approved uses

From the indications section of the FDA label (version of Dec 9, 2025). Read the full label for the exact wording, limitations and safety information.

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT07762794 Phase 4 Vascular Injury Not yet recruiting HUMA
NCT07762313 Phase 3 Vascular Trauma Not yet recruiting HUMA
NCT05908084 Phase 3 End Stage Renal Disease (ESRD) Active not recruiting HUMA
NCT02644941 Phase 3 Renal Failure Completed HUMA
NCT04135417 Phase 2 Renal Failure Completed HUMA
NCT05873959 N/A Trauma Completed HUMA
NCT03631056 N/A Vascular System Injuries Approved for marketing HUMA

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Arterial BleedingArterial InjuryEnd Stage Renal Disease (ESRD)Vascular InjuryVascular TraumaEnd Stage Renal DiseaseHemodialysisRenal FailureTraumaTrauma BluntTrauma InjuryTrauma, MultipleVascular AccessVascular System Injuries

More from Humacyte Global

Sources

Updated Oct 3, 2026. Something wrong or missing? Report it on the HUMA page.

Follow HUMA, the company behind Acellular Tissue Engineered Vessel

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.