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131I-apamistamab

Radiopharmaceutical · Kills target cells, directed at CD45 (PTPRC) · developed by Actinium Pharmaceuticals

Phase 2/3 Most advanced trial
ATNM Developer
1 Registered trials

What is 131I-apamistamab?

131I-apamistamab is an iodine-131 radiolabeled anti-CD45 monoclonal antibody. It binds CD45, a protein on leukocytes, delivering targeted radiation, and is studied in acute myeloid leukemia, including relapsed or refractory disease and transplant-related settings.

Summary written with AI from the sources listed at the end of this page.

At a glance

Drug type
Radiopharmaceutical
Targets
CD45 (PTPRC)
Mechanism
Kills target cells, directed at CD45 (PTPRC)
Therapy area
Oncology
Developer
Actinium Pharmaceuticals (ATNM)
FDA status
Investigational, not approved in the US. Most advanced trial: Phase 2/3

🧪 Clinical trials

TrialPhaseConditionStatusSponsor
NCT07157514 Phase 2/3 Acute Leukemia Not yet recruiting ATNM

Trials of the companies BioRadar tracks, from ClinicalTrials.gov, most advanced phase first.

Conditions studied

Acute LeukemiaAcute Myelogenous LeukemiaAcute Myeloid LeukemiaAcute Myeloid Leukemia, in RelapseAllogeneic DiseaseMyelogenous LeukemiaMyelogenous Leukemia in RelapseMyelogenous Leukemia, AcuteMyeloid LeukemiaRefractory AMLTransplant-Related Disorder

Other drugs acting on PTPRC

More from Actinium Pharmaceuticals

Sources

Updated Oct 11, 2026. Something wrong or missing? Report it on the ATNM page.

Follow ATNM, the company behind 131I-apamistamab

See ATNM's upcoming FDA decisions, trial readouts, cash runway and dilution risk, updated every day from SEC, FDA and ClinicalTrials.gov filings.

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Data: FDA (Drugs@FDA, Purple Book, DailyMed), NIH (NCI Thesaurus, GSRS, RxNorm), ClinicalTrials.gov • Informational purposes only, not medical or investment advice. • All drugs A–Z

This data is for informational purposes only, not investment advice. BioRadar does not provide buy/sell recommendations. Past performance does not guarantee future results. Always do your own due diligence.